We aim to understand population cell heterogeneity and relevance in microenvironment-cell interactions during epithelial to mesenchymal transitions. Epithelial to mesenchymal transition is a shift in cell morphology, molecular biology associated with developmental process, tissue regeneration and cancer. We use interdisciplinary approach aiming at an integrative understanding of the model of ovarian cancer cell physiology within their microenvironment. We do imaging of tumor morphological dynamics combining superresolution microscopy and quantitative biology. We use microscopy modalities in combination with genetic tools and targeted perturbation to tune cell-microenvironment interactions. We seek to apply the knowledge gain in fundamental cell biology, tissue engineering, regenerative medicine and cancer drug development.

Ambroise Lambert is leading his own research in the laboratory of Cell-Microenvironment Relationship:

for further informations: https://errmece.cyu.fr/, https://errmece.u-cergy.fr/, https://errmece.u-cergy.fr/?page_id=3708.